Return the selected gene list signatures — getGeneSignatures • splitTypeR

The function returns the selected gene list signatures.

getGeneSignatures(nameList = NULL)

Arguments

nameList: a list of signature names. At least one name is required. The signature names must all be present in the gene list signatures. When NULL, all gene signatures are returned. Default: NULL.

Value

a list of selected signatures. Each signature is composed of a vector of gene names.

Details

The PDAC PDO classical and basal-like signatures are associated to this publication:

Tiriac et al. Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer. Cancer Discov. 2018 Sep;8(9):1112-1129. doi: 10.1158/2159-8290.CD-18-0349. Epub 2018 May 31. PMID: 29853643; PMCID: PMC6125219.

Author

Astrid Deschênes

Examples


## Extract the basal-like signature from Tiriac et al 2018
getGeneSignatures(nameList=c("2018_Tiriac_PDAC_PDO_basal-like_signature"))
#> $`2018_Tiriac_PDAC_PDO_basal-like_signature`
#>  [1] "ANO1"     "ADORA2B"  "S100A2"   "CSF2"     "ANXA1"    "EREG"    
#>  [7] "RGS20"    "CELSR1"   "WNT7B"    "AMIGO2"   "PTHLH"    "C12orf54"
#> [13] "TGM2"     "REEP3"    "DCBLD2"   "NMB"      "IKZF2"    "GPR87"   
#> [19] "MUC16"    "IVL"      "SPRR1B"   "BCAR3"    "TTC9"     "PTGES"   
#> [25] "CST6"     "CATSPER1"
#>