Create a density plot using the relative AUC and the sensitivity classes (SENSITIVE, AVERAGE, RESISTANT) of the organoids for a specific drug.

The function generates a density plot using the relative AUC and the sensitivity class information present in a DrugAUCQuantile" object. The function uses [ggplot2::ggplot][ggplot2::ggplot()] function and returns a "ggplot" object. The density plot can be split by sensitivity classes.

plotDrugAUCDensityCurve(drugQuantile, byGroup = FALSE)

Arguments

drugQuantile

an object of class "DrugAUCQuantile" which contains the sensitive and resistant information for organoids associated to a specific drug screening.

byGroup

a logical indicating if the density is split by group. Default: FALSE.

Value

a ggplot object that represents a density plot of the AUC according to the drug sensitivity classification(SENSITIVE, AVERAGE, RESISTANT).

Author

Astrid Deschênes, Pascal Belleau

Examples

## Load drug screen dataset for 1 drug
data(drugScreening)

## Calculate the extreme organoids for the methotrexate drug screening
## using a quantile of 1/3
results <- getClassOneDrug(drugScreening=drugScreening,
    drugName="Methotrexate", study="MEGA-TEST", screenType="TEST-01",
    doseType="Averaged", quantile=1/3)

## Create a density plot where drug sensitivy groups are split
densityGraph <- plotDrugAUCDensityCurve(results, byGroup=TRUE)
densityGraph
#> Picking joint bandwidth of 3.58